Product name: Apaurine 10mg

Active substance: Diazepam

Dosage Strength: 10 MG

Quantity: 170 – 750 Capsules





Apaurine is medicine that contains an active substance called diazepam. This medicine belongs to group of medicines called benzodiazepines. It has sedative and relaxing effects, and therefore it is used in the treatment of

  1. anxiety,

  2. insomnia,

  3. epilepsy,

  4. muscle cramps (muscle spasms),

  5. to relieve symptoms in patients in alcohol rehab and in preparing patients for surgery.


It should not be used for more than one month, because of the risk of addiction! Apaurine may cause a psychological and physical dependence, especially if it is used in higher doses and for more than a month. Your doctor will determine the duration of treatment with this medicine.

Do not stop using this drug, as it may cause “withdrawal syndrome” or worsening of your symptoms (anxiety, insomnia, mood changes, seizures, etc.)! You should stop using this drug slowly.

We’ll give you an example: If you are taking Apaurine 10 mg, it is necessary to first reduce the dose to 5 mg for 4-5 days, and then again reduce the dose to 2 mg for 4-5 days, after what you can completely stop with using.

After prolonged use tolerance on this drug can develop, respectively Apaurine will have less effect on the patient.

It should be avoided in combination with alcoholic beverages because alcohol can increase the effect of this drug!

It should be avoided in patients with myasthenia gravis (autoimmune neuromuscular disorder) because Apaurine may worsen the condition in such patients.

Bear in mind that it can cause anterograde amnesia (inability to recall events that occurred while you were under the influence of the drug). Therefore it should be taken 30 minutes / one hour before bedtime.

Apaurine should not be used in patients with severe liver disorders or severe kidney disorders.

It may have increased effect in elderly patients and cause dizziness, which can lead to falls of elderly patients and different types of injuries. Therefore, it should be used only with extra precautions in elderly patients.

Apaurine should be avoided in patients allergic to diazepam or other similar drugs: bromazepam, nitrazepam, lorazepam and others.

This drug is not intended for use in people who have experienced the loss of a loved one, because Apaurine may disturb the mental adjustment. Also, it is not intended for use in paitents with mental disorders.


Use of Apaurine is not recommended during pregnancy, especially during the first and last trimester, because it can cause cleft lip in babies or cause the fetus to become addicted! This medicine can be used during pregnancy only if the benefit to the mother outweighs the risk to the child.

Avoid breastfeeding while using this drug, because Apaurine passes into breast milk and may harm your baby.


It should be used at the lowest effective dose. Your doctor will determine which dose of Apaurine will suit you best.

Dose used in the treatment of anxiety is Apaurine 5-30 mg, divided into multiple doses during the day. The initial dose is usually 2 mg, three times a day. Dosage can be increased until desired effect is achieved.

Dose used in the treatment of insomnia is 5-10 mg, half an hour before bedtime.

In the treatment of muscle cramps dose is 5-15 mg, divided into multiple doses during the day.

In elderly patients (above the age of 65), the dose should be 50% lower than in adults.

Apaurin should not be used for more than a month. Abrupt discontinuation should be avoided. When stopping the treatment with this medicine the dose should be gradually reduced over a period of at least one to two weeks.


It may cause the following side effects:

  1. mood changes,

  2. confusion,

  3. restlessness,

  4. tension,

  5. anxiety,

  6. headache,

  7. dizziness,

  8. behavior changes,

  9. increased sensitivity to light,

  10. increased sensitivity to sound,

  11. convulsions (seizures).

All these symptoms may occur if you stop using Apaurine abruptly!

Apaurine may also cause the following side effects:

  1. nausea,

  2. constipation,

  3. liver damage that accompanies with jaundice (yellowing of the skin and eyes),

  4. double vision,

  5. hypotension (low blood pressure),

  6. arrhythmia (irregular heartbeat),

  7. chest pains

  8. anterograde amnesia (inability to recall events that occurred while you were under the influence of the drug),

  9. difficulty breathing,

  10. slow breathing,

  11. fatigue,

  12. hallucinations,

  13. urinating problems,

  14. breast enlargement in men (gynecomastia),

allergy and others.


Apaurine should be avoided in combination with the following medications:

All drugs that have effects on the central nervous system, such as:

  1. antipsychotics,

  2. anxiolytics,

  3. antidepressants,

  4. analgesics,

anesthetics, and other. Concomitant use with these drugs may increase the effect of Apaurine on the central nervous system! Tell your doctor about all medicines you are taking.

Drugs used in the treatment of fungal infections, such as:

  1. fluconazole,

  2. ketoconazole,

  3. itraconazole, and others.

Drugs used in the treatment of bacterial infections (antibiotics), such as:

  1. erythromycin,

  2. clarithromycin,

  3. azithromycin, and others. Concomitant use with these drugs may lead to increased effects of Apaurine.

Drugs used in the treatment of HIV (AIDS), such as:

  1. ritonavir,

  2. saquinavir,

  3. indinavir,

  4. nelfinavir, and others.

  5. Rifampicin, used to treat tuberculosis.

Drugs used in the treatment of heart disease, such as:

  1. diltiazem,

  2. verapamil, and others. Apaurine may increase the effect of these drugs and cause hypotension (low blood pressure).

Drugs used in the treatment of high blood pressure and benign prostate enlargement (alpha blockers), such as:

  1. prazosin,

  2. terazosin,

  3. doxazosin, and others. These drugs may increase the effect of Apaurine.

Drugs used to treat epilepsy:

  1. phenobarbital,

  2. phenytoin.

  3. Drugs used to treat severe pain (opioid analgesics), such as:

  4. morphine,

  5. tramadol, and others. Concomitant use of these drugs increases the risk of side effects.

Medicines used to treat allergy (antihistamines):

  1. dimenhydrinate,

  2. loratadine and others.

Drugs used in the treatment of ulcer and heartburn, such as: omeprazole (Omeprol).

Apaurine should be avoided in combination with alcoholic beverages or grapefruit juice, as these foods may hamper the effects of Apaurine.


Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient.

Inspire Health Pharmacy does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.


Here at Inspire Health Pharmacy we sell the best quality APAURINE and top quality pills.

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We only use plain, discreet packaging without any branding or labels. In most cases package is sent as a gift in case of bigger packaging to rapidly aviate custom checks.


100% delivery success rate with rapid delivery. 24hrs express and custom delivery ranging from 3-8 business days.


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